Google just announced its ad exchange:
The DoubleClick Ad Exchange is a real-time marketplace to buy and sell display advertising space. By establishing an open marketplace where prices are set in a real-time auction, the Ad Exchange enables display ads and ad space to be allocated much more efficiently and easily across the web. It’s just like a stock exchange, which enables stocks to be traded in an open way.
There are some existing competitors, but Google’s entry may be game-changing. Lots of research problems beg themselves.

September 18, 2009 at 2:47 pm |
Another competitor, but aimed at small webcomic sites instead of large sites: http://www.projectwonderful.com/
October 8, 2009 at 10:41 am |
Does this mean that prediction markets for words like this one http://pretweeting.com/ could now be valuable? If someone can predict in advance what words will get popular could they make money?